| So., 21.05.2000 | VfL Bochum - Chemnitzer FC | 5:1 |
| So., 21.05.2000 | SV Waldhof Mannheim - SC Fortuna Köln | 1:3 |
| So., 21.05.2000 | 1. FC Köln - FC St. Pauli | 6:3 |
| So., 21.05.2000 | Rot-Weiß Oberhausen - Alemannia Aachen | 3:0 |
| So., 21.05.2000 | SpVgg Greuther Fürth - Karlsruher SC | 2:0 |
| So., 21.05.2000 | Stuttgarter Kickers - Hannover 96 | 2:1 |
| So., 21.05.2000 | Tennis Borussia Berlin - 1. FC Nürnberg | 1:3 |
| So., 21.05.2000 | Borussia Mönchengladbach - FSV Mainz 05 | 6:1 |
| So., 21.05.2000 | Kickers Offenbach - FC Energie Cottbus | 1:2 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | 1. FC Köln | 33 | 19-8-6 | 68:37 | 31 | 65 |
| 2. | |  | VfL Bochum | 33 | 18-6-9 | 64:45 | 19 | 60 |
| 3. | |  | FC Energie Cottbus | 33 | 17-4-12 | 60:42 | 18 | 55 |
| 4. | |  | Borussia Mönchengladbach | 33 | 14-12-7 | 59:41 | 18 | 54 |
| 5. | |  | 1. FC Nürnberg | 33 | 14-10-9 | 52:45 | 7 | 52 |
| 6. | |  | Rot-Weiß Oberhausen | 33 | 12-12-9 | 42:33 | 9 | 48 |
| 7. |  |  | SpVgg Greuther Fürth | 33 | 10-15-8 | 38:37 | 1 | 45 |
| 8. |  |  | Alemannia Aachen | 33 | 12-9-12 | 44:52 | -8 | 45 |
| 9. | |  | Hannover 96 | 33 | 12-7-14 | 53:53 | 0 | 43 |
| 10. | |  | FSV Mainz 05 | 33 | 10-12-11 | 39:42 | -3 | 42 |
| 11. | |  | SV Waldhof Mannheim | 33 | 10-12-11 | 50:54 | -4 | 42 |
| 12. | |  | Tennis Borussia Berlin | 33 | 10-10-13 | 42:49 | -7 | 40 |
| 13. | |  | Chemnitzer FC | 33 | 10-10-13 | 41:49 | -8 | 40 |
| 14. | |  | FC St. Pauli | 33 | 8-14-11 | 36:44 | -8 | 38 |
| 15. | |  | Stuttgarter Kickers | 33 | 10-8-15 | 48:57 | -9 | 38 |
| 16. | |  | Kickers Offenbach | 33 | 8-11-14 | 34:54 | -20 | 35 |
| 17. | |  | SC Fortuna Köln | 33 | 7-11-15 | 34:49 | -15 | 32 |
| 18. | |  | Karlsruher SC | 33 | 5-11-17 | 34:55 | -21 | 26 |