| Sa., 16.05.1981 | 1. FC Magdeburg - FC Vorwärts Frankfurt/O. | 4:1 |
| Sa., 16.05.1981 | BSG Chemie Böhlen - BSG Stahl Riesa | 1:1 |
| Sa., 16.05.1981 | FC Hansa Rostock - FC Carl Zeiss Jena | 1:3 |
| Sa., 16.05.1981 | FC Karl-Marx-Stadt - HFC Chemie | 2:2 |
| Sa., 16.05.1981 | FC Rot-Weiß Erfurt - BSG Sachsenring Zwickau | 2:1 |
| Sa., 16.05.1981 | BSG Wismut Aue - 1. FC Lok Leipzig | 0:2 |
| Sa., 16.05.1981 | SG Dynamo Dresden - BFC Dynamo | 3:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | BFC Dynamo | 24 | 15-5-4 | 68:29 | 39 | 35 - 13 |
| 2. | |  | FC Carl Zeiss Jena | 24 | 15-4-5 | 53:26 | 27 | 34 - 14 |
| 3. | |  | 1. FC Magdeburg | 24 | 15-4-5 | 56:31 | 25 | 34 - 14 |
| 4. | |  | SG Dynamo Dresden | 24 | 15-2-7 | 46:34 | 12 | 32 - 16 |
| 5. | |  | FC Vorwärts Frankfurt/O. | 24 | 11-5-8 | 50:38 | 12 | 27 - 21 |
| 6. | |  | FC Rot-Weiß Erfurt | 24 | 10-7-7 | 35:42 | -7 | 27 - 21 |
| 7. | |  | 1. FC Lok Leipzig | 24 | 11-4-9 | 41:28 | 13 | 26 - 22 |
| 8. | |  | HFC Chemie | 24 | 9-3-12 | 38:40 | -2 | 21 - 27 |
| 9. | |  | FC Hansa Rostock | 24 | 6-8-10 | 33:42 | -9 | 20 - 28 |
| 10. | |  | FC Karl-Marx-Stadt | 24 | 5-9-10 | 31:52 | -21 | 19 - 29 |
| 11. |  |  | BSG Chemie Böhlen | 24 | 5-6-13 | 24:44 | -20 | 16 - 32 |
| 12. |  |  | BSG Wismut Aue | 24 | 6-4-14 | 31:54 | -23 | 16 - 32 |
| 13. | |  | BSG Stahl Riesa | 24 | 5-5-14 | 35:59 | -24 | 15 - 33 |
| 14. | |  | BSG Sachsenring Zwickau | 24 | 5-4-15 | 28:50 | -22 | 14 - 34 |