| Sa., 04.10.1980 | BSG Chemie Böhlen - FC Karl-Marx-Stadt | 1:1 |
| Sa., 04.10.1980 | BSG Sachsenring Zwickau - 1. FC Lok Leipzig | 0:3 |
| Sa., 04.10.1980 | HFC Chemie - FC Vorwärts Frankfurt/O. | 2:3 |
| Sa., 04.10.1980 | FC Carl Zeiss Jena - 1. FC Magdeburg | 2:3 |
| Sa., 04.10.1980 | BSG Stahl Riesa - BSG Wismut Aue | 2:2 |
| Sa., 04.10.1980 | BFC Dynamo - FC Rot-Weiß Erfurt | 7:1 |
| Sa., 04.10.1980 | FC Hansa Rostock - SG Dynamo Dresden | 1:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | FC Carl Zeiss Jena | 7 | 6-0-1 | 19:9 | 10 | 12 - 2 |
| 2. |  |  | BFC Dynamo | 7 | 5-1-1 | 23:5 | 18 | 11 - 3 |
| 3. | |  | 1. FC Magdeburg | 7 | 5-1-1 | 20:7 | 13 | 11 - 3 |
| 4. |  |  | SG Dynamo Dresden | 7 | 5-1-1 | 13:8 | 5 | 11 - 3 |
| 5. | |  | 1. FC Lok Leipzig | 7 | 4-1-2 | 14:8 | 6 | 9 - 5 |
| 6. | |  | BSG Chemie Böhlen | 7 | 4-1-2 | 9:7 | 2 | 9 - 5 |
| 7. | |  | FC Vorwärts Frankfurt/O. | 7 | 2-3-2 | 12:12 | 0 | 7 - 7 |
| 8. | |  | FC Hansa Rostock | 7 | 1-4-2 | 7:9 | -2 | 6 - 8 |
| 9. | |  | BSG Wismut Aue | 7 | 2-2-3 | 6:12 | -6 | 6 - 8 |
| 10. | |  | FC Karl-Marx-Stadt | 7 | 1-3-3 | 7:11 | -4 | 5 - 9 |
| 11. | |  | HFC Chemie | 7 | 2-0-5 | 13:18 | -5 | 4 - 10 |
| 12. | |  | BSG Stahl Riesa | 7 | 0-3-4 | 8:19 | -11 | 3 - 11 |
| 13. | |  | FC Rot-Weiß Erfurt | 7 | 1-1-5 | 8:21 | -13 | 3 - 11 |
| 14. | |  | BSG Sachsenring Zwickau | 7 | 0-1-6 | 5:18 | -13 | 1 - 13 |