| Fr., 05.05.2000 | Karlsruher SC - FC St. Pauli | 0:0 |
| Fr., 05.05.2000 | Alemannia Aachen - FC Energie Cottbus | 1:0 |
| Sa., 06.05.2000 | SC Fortuna Köln - VfL Bochum | 2:3 |
| So., 07.05.2000 | 1. FC Nürnberg - SpVgg Greuther Fürth | 2:2 |
| So., 07.05.2000 | Chemnitzer FC - Rot-Weiß Oberhausen | 1:1 |
| So., 07.05.2000 | Kickers Offenbach - Tennis Borussia Berlin | 2:1 |
| So., 07.05.2000 | FSV Mainz 05 - Stuttgarter Kickers | 2:0 |
| Mo., 08.05.2000 | Hannover 96 - 1. FC Köln | 3:5 |
| Mi., 10.05.2000 | SV Waldhof Mannheim - Borussia Mönchengladbach | 2:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | 1. FC Köln | 30 | 17-8-5 | 59:31 | 28 | 59 |
| 2. | |  | VfL Bochum | 30 | 16-6-8 | 58:43 | 15 | 54 |
| 3. | |  | FC Energie Cottbus | 30 | 14-4-12 | 52:37 | 15 | 46 |
| 4. |  |  | 1. FC Nürnberg | 30 | 12-10-8 | 46:43 | 3 | 46 |
| 5. |  |  | Borussia Mönchengladbach | 30 | 11-12-7 | 50:39 | 11 | 45 |
| 6. | |  | Alemannia Aachen | 30 | 12-9-9 | 42:45 | -3 | 45 |
| 7. | |  | Hannover 96 | 30 | 12-7-11 | 50:47 | 3 | 43 |
| 8. | |  | SV Waldhof Mannheim | 30 | 10-12-8 | 45:45 | 0 | 42 |
| 9. | |  | Tennis Borussia Berlin | 30 | 10-10-10 | 39:42 | -3 | 40 |
| 10. | |  | Rot-Weiß Oberhausen | 30 | 9-12-9 | 34:32 | 2 | 39 |
| 11. | |  | SpVgg Greuther Fürth | 30 | 8-15-7 | 34:35 | -1 | 39 |
| 12. | |  | FSV Mainz 05 | 30 | 8-12-10 | 35:35 | 0 | 36 |
| 13. | |  | Chemnitzer FC | 30 | 9-9-12 | 38:43 | -5 | 36 |
| 14. | |  | FC St. Pauli | 30 | 7-14-9 | 29:34 | -5 | 35 |
| 15. | |  | Stuttgarter Kickers | 30 | 9-7-14 | 45:52 | -7 | 34 |
| 16. | |  | Kickers Offenbach | 30 | 7-11-12 | 30:49 | -19 | 32 |
| 17. | |  | SC Fortuna Köln | 30 | 5-11-14 | 28:45 | -17 | 26 |
| 18. | |  | Karlsruher SC | 30 | 4-11-15 | 32:49 | -17 | 23 |