| Sa., 13.09.1980 | FC Rot-Weiß Erfurt - FC Karl-Marx-Stadt | 3:2 |
| Sa., 13.09.1980 | 1. FC Magdeburg - BSG Chemie Böhlen | 2:0 |
| Sa., 13.09.1980 | FC Vorwärts Frankfurt/O. - BFC Dynamo | 2:1 |
| Sa., 13.09.1980 | 1. FC Lok Leipzig - BSG Stahl Riesa | 3:0 |
| Sa., 13.09.1980 | BSG Sachsenring Zwickau - FC Carl Zeiss Jena | 0:3 |
| Sa., 13.09.1980 | BSG Wismut Aue - FC Hansa Rostock | 1:0 |
| Sa., 13.09.1980 | SG Dynamo Dresden - HFC Chemie | 3:2 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | FC Carl Zeiss Jena | 4 | 4-0-0 | 13:4 | 9 | 8 - 0 |
| 2. | |  | 1. FC Magdeburg | 4 | 3-0-1 | 11:3 | 8 | 6 - 2 |
| 3. |  |  | BFC Dynamo | 4 | 3-0-1 | 10:3 | 7 | 6 - 2 |
| 4. |  |  | SG Dynamo Dresden | 4 | 3-0-1 | 7:4 | 3 | 6 - 2 |
| 5. | |  | 1. FC Lok Leipzig | 4 | 2-1-1 | 7:5 | 2 | 5 - 3 |
| 6. | |  | BSG Wismut Aue | 4 | 2-1-1 | 4:4 | 0 | 5 - 3 |
| 7. | |  | FC Vorwärts Frankfurt/O. | 4 | 1-2-1 | 7:7 | 0 | 4 - 4 |
| 8. | |  | FC Hansa Rostock | 4 | 1-2-1 | 5:5 | 0 | 4 - 4 |
| 9. | |  | BSG Chemie Böhlen | 4 | 2-0-2 | 5:6 | -1 | 4 - 4 |
| 10. | |  | HFC Chemie | 4 | 1-0-3 | 6:10 | -4 | 2 - 6 |
| 11. | |  | FC Rot-Weiß Erfurt | 4 | 1-0-3 | 6:11 | -5 | 2 - 6 |
| 12. | |  | FC Karl-Marx-Stadt | 4 | 0-2-2 | 3:8 | -5 | 2 - 6 |
| 13. | |  | BSG Stahl Riesa | 4 | 0-1-3 | 4:11 | -7 | 1 - 7 |
| 14. | |  | BSG Sachsenring Zwickau | 4 | 0-1-3 | 1:8 | -7 | 1 - 7 |