| Sa., 18.10.1980 | FC Karl-Marx-Stadt - BFC Dynamo | 1:2 |
| Sa., 18.10.1980 | 1. FC Magdeburg - HFC Chemie | 1:0 |
| Sa., 18.10.1980 | FC Vorwärts Frankfurt/O. - BSG Sachsenring Zwickau | 6:1 |
| Sa., 18.10.1980 | FC Hansa Rostock - BSG Chemie Böhlen | 2:0 |
| Sa., 18.10.1980 | FC Rot-Weiß Erfurt - BSG Stahl Riesa | 2:0 |
| Sa., 18.10.1980 | BSG Wismut Aue - FC Carl Zeiss Jena | 1:4 |
| Sa., 18.10.1980 | SG Dynamo Dresden - 1. FC Lok Leipzig | 2:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | FC Carl Zeiss Jena | 8 | 7-0-1 | 23:10 | 13 | 14 - 2 |
| 2. | |  | BFC Dynamo | 8 | 6-1-1 | 25:6 | 19 | 13 - 3 |
| 3. | |  | 1. FC Magdeburg | 8 | 6-1-1 | 21:7 | 14 | 13 - 3 |
| 4. | |  | SG Dynamo Dresden | 8 | 6-1-1 | 15:9 | 6 | 13 - 3 |
| 5. |  |  | FC Vorwärts Frankfurt/O. | 8 | 3-3-2 | 18:13 | 5 | 9 - 7 |
| 6. |  |  | 1. FC Lok Leipzig | 8 | 4-1-3 | 15:10 | 5 | 9 - 7 |
| 7. | |  | BSG Chemie Böhlen | 8 | 4-1-3 | 9:9 | 0 | 9 - 7 |
| 8. | |  | FC Hansa Rostock | 8 | 2-4-2 | 9:9 | 0 | 8 - 8 |
| 9. | |  | BSG Wismut Aue | 8 | 2-2-4 | 7:16 | -9 | 6 - 10 |
| 10. | |  | FC Karl-Marx-Stadt | 8 | 1-3-4 | 8:13 | -5 | 5 - 11 |
| 11. | |  | FC Rot-Weiß Erfurt | 8 | 2-1-5 | 10:21 | -11 | 5 - 11 |
| 12. | |  | HFC Chemie | 8 | 2-0-6 | 13:19 | -6 | 4 - 12 |
| 13. | |  | BSG Stahl Riesa | 8 | 0-3-5 | 8:21 | -13 | 3 - 13 |
| 14. | |  | BSG Sachsenring Zwickau | 8 | 0-1-7 | 6:24 | -18 | 1 - 15 |