| Sa., 30.10.2010 | Chemnitzer FC II - FSV 63 Luckenwalde | 0:2 |
| Sa., 30.10.2010 | VfB Auerbach - 1. FC Magdeburg II | 3:1 |
| So., 31.10.2010 | FC Carl Zeiss Jena II - FSV Budissa Bautzen | 2:2 |
| So., 31.10.2010 | FC Erzgebirge Aue II - 1. FC Lok Leipzig | 1:0 |
| So., 31.10.2010 | FC Sachsen Leipzig - SC Borea Dresden | 0:1 |
| So., 31.10.2010 | VfL Halle 96 - FSV Zwickau | 1:1 |
| So., 31.10.2010 | FC Rot-Weiß Erfurt II - FSV Wacker 03 Gotha | 0:0 |
| So., 31.10.2010 | SG Dynamo Dresden II - VfB Germania Halberstadt | 1:3 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | VfB Auerbach | 10 | 7-1-2 | 18:13 | 5 | 22 |
| 2. |  |  | VfB Germania Halberstadt | 10 | 5-4-1 | 19:10 | 9 | 19 |
| 3. |  |  | FC Rot-Weiß Erfurt II | 10 | 5-4-1 | 20:13 | 7 | 19 |
| 4. | |  | FSV Budissa Bautzen | 10 | 5-4-1 | 15:8 | 7 | 19 |
| 5. | |  | FSV 63 Luckenwalde | 10 | 4-3-3 | 20:15 | 5 | 15 |
| 6. | |  | FSV Zwickau | 9 | 4-3-2 | 16:12 | 4 | 15 |
| 7. | |  | SC Borea Dresden | 9 | 4-3-2 | 10:10 | 0 | 15 |
| 8. | |  | FC Erzgebirge Aue II | 9 | 4-2-3 | 14:7 | 7 | 14 |
| 9. | |  | FC Carl Zeiss Jena II | 10 | 2-5-3 | 15:15 | 0 | 11 |
| 10. | |  | FC Sachsen Leipzig | 8 | 3-2-3 | 7:9 | -2 | 11 |
| 11. | |  | SG Dynamo Dresden II | 10 | 3-1-6 | 11:15 | -4 | 10 |
| 12. | |  | FSV Wacker 03 Gotha | 10 | 2-3-5 | 12:18 | -6 | 9 |
| 13. | |  | 1. FC Magdeburg II | 10 | 2-3-5 | 11:21 | -10 | 9 |
| 14. | |  | 1. FC Lok Leipzig | 8 | 1-5-2 | 11:12 | -1 | 8 |
| 15. | |  | VfL Halle 96 | 9 | 1-3-5 | 9:16 | -7 | 6 |
| 16. | |  | Chemnitzer FC II | 10 | 0-2-8 | 10:24 | -14 | 2 |