| Fr., 16.09.2022 | BFC Dynamo - Hertha BSC Berlin II | 0:0 |
| Fr., 16.09.2022 | FSV 63 Luckenwalde - SV Lichtenberg 47 | 1:1 |
| Fr., 16.09.2022 | VSG Altglienicke - ZFC Meuselwitz | 5:2 |
| Sa., 17.09.2022 | BSG Chemie Leipzig - Berliner AK 07 | 2:1 |
| Sa., 17.09.2022 | FC Energie Cottbus - Chemnitzer FC | 3:1 |
| So., 18.09.2022 | VfB Germania Halberstadt - 1. FC Lok Leipzig | 1:3 |
| So., 18.09.2022 | Greifswalder FC - FC Viktoria 1889 Berlin | 5:0 |
| So., 18.09.2022 | Tennis Borussia Berlin - SV Babelsberg 03 | 0:1 |
| So., 18.09.2022 | FC Rot-Weiß Erfurt - FC Carl Zeiss Jena | 1:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | Berliner AK 07 | 6 | 5-0-1 | 9:3 | 6 | 15 |
| 2. | |  | FC Carl Zeiss Jena | 6 | 4-2-0 | 13:2 | 11 | 14 |
| 3. |  |  | VSG Altglienicke | 6 | 4-2-0 | 14:7 | 7 | 14 |
| 4. |  |  | SV Babelsberg 03 | 6 | 4-2-0 | 10:5 | 5 | 14 |
| 5. | |  | FC Rot-Weiß Erfurt | 6 | 3-2-1 | 14:4 | 10 | 11 |
| 6. | |  | 1. FC Lok Leipzig | 6 | 3-2-1 | 14:8 | 6 | 11 |
| 7. | |  | FC Energie Cottbus | 6 | 3-1-2 | 11:5 | 6 | 10 |
| 8. | |  | BSG Chemie Leipzig | 6 | 3-1-2 | 11:11 | 0 | 10 |
| 9. | |  | Hertha BSC Berlin II | 6 | 2-2-2 | 10:11 | -1 | 8 |
| 10. | |  | Chemnitzer FC | 6 | 2-2-2 | 6:7 | -1 | 8 |
| 11. | |  | Greifswalder FC | 6 | 2-1-3 | 9:6 | 3 | 7 |
| 12. | |  | FSV 63 Luckenwalde | 6 | 0-5-1 | 7:10 | -3 | 5 |
| 13. | |  | BFC Dynamo | 6 | 1-2-3 | 2:5 | -3 | 5 |
| 14. | |  | FC Viktoria 1889 Berlin | 6 | 1-2-3 | 7:13 | -6 | 5 |
| 15. | |  | SV Lichtenberg 47 | 6 | 1-2-3 | 5:11 | -6 | 5 |
| 16. | |  | ZFC Meuselwitz | 6 | 1-0-5 | 7:16 | -9 | 3 |
| 17. | |  | VfB Germania Halberstadt | 6 | 0-1-5 | 3:13 | -10 | 1 |
| 18. | |  | Tennis Borussia Berlin | 6 | 0-1-5 | 4:19 | -15 | 1 |