| Fr., 26.09.2025 | 1. FC Lok Leipzig - SV Babelsberg 03 | 1:0 |
| Fr., 26.09.2025 | Hertha BSC Berlin II - FC Rot-Weiß Erfurt | 0:0 |
| Sa., 27.09.2025 | BFC Preussen - 1. FC Magdeburg II | 1:0 |
| Sa., 27.09.2025 | FC Eilenburg - Hertha 03 Zehlendorf | 1:1 |
| Sa., 27.09.2025 | FSV 63 Luckenwalde - BSG Chemie Leipzig | 1:0 |
| Sa., 27.09.2025 | FC Carl Zeiss Jena - Chemnitzer FC | 2:0 |
| So., 28.09.2025 | FSV Zwickau - Hallescher FC | 2:1 |
| So., 28.09.2025 | VSG Altglienicke - BFC Dynamo | 0:0 |
| So., 28.09.2025 | ZFC Meuselwitz - Greifswalder FC | 1:1 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | FC Carl Zeiss Jena | 10 | 8-1-1 | 20:3 | 17 | 25 |
| 2. |  |  | 1. FC Lok Leipzig | 10 | 8-1-1 | 19:5 | 14 | 25 |
| 3. | |  | FC Rot-Weiß Erfurt | 10 | 7-2-1 | 22:13 | 9 | 23 |
| 4. | |  | VSG Altglienicke | 10 | 7-1-2 | 16:7 | 9 | 22 |
| 5. |  |  | Hallescher FC | 10 | 6-1-3 | 15:9 | 6 | 19 |
| 6. | |  | FSV Zwickau | 10 | 5-3-2 | 12:11 | 1 | 18 |
| 7. | |  | FSV 63 Luckenwalde | 10 | 6-0-4 | 14:14 | 0 | 18 |
| 8. | |  | BFC Preussen | 10 | 4-3-3 | 12:13 | -1 | 15 |
| 9. | |  | Chemnitzer FC | 10 | 4-2-4 | 13:13 | 0 | 14 |
| 10. | |  | 1. FC Magdeburg II | 10 | 4-1-5 | 17:14 | 3 | 13 |
| 11. | |  | SV Babelsberg 03 | 10 | 4-1-5 | 15:14 | 1 | 13 |
| 12. | |  | ZFC Meuselwitz | 10 | 2-4-4 | 9:14 | -5 | 10 |
| 13. | |  | Hertha BSC Berlin II | 10 | 1-6-3 | 17:21 | -4 | 9 |
| 14. | |  | BFC Dynamo | 10 | 2-3-5 | 12:18 | -6 | 9 |
| 15. | |  | Greifswalder FC | 10 | 1-3-6 | 9:16 | -7 | 6 |
| 16. | |  | FC Eilenburg | 10 | 1-3-6 | 9:20 | -11 | 6 |
| 17. | |  | BSG Chemie Leipzig | 10 | 1-1-8 | 5:15 | -10 | 4 |
| 18. | |  | Hertha 03 Zehlendorf | 10 | 0-2-8 | 5:21 | -16 | 2 |