| Sa., 19.02.2011 | FSV Zwickau - FSV Budissa Bautzen | 1:0 |
| Sa., 19.02.2011 | FSV Wacker 03 Gotha - Chemnitzer FC II | 0:1 |
| Sa., 19.02.2011 | FC Rot-Weiß Erfurt II - FC Carl Zeiss Jena II | 1:0 |
| Sa., 19.02.2011 | VfL Halle 96 - SG Dynamo Dresden II | 3:0 |
| Sa., 19.02.2011 | SC Borea Dresden - VfB Germania Halberstadt | 1:1 |
| Sa., 19.02.2011 | VfB Auerbach - FSV 63 Luckenwalde | 7:0 |
| So., 20.02.2011 | 1. FC Magdeburg II - 1. FC Lok Leipzig | 0:4 |
| So., 20.02.2011 | FC Sachsen Leipzig - FC Erzgebirge Aue II | 0:2 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | VfB Auerbach | 16 | 10-3-3 | 34:18 | 16 | 33 |
| 2. |  |  | FSV Budissa Bautzen | 16 | 9-4-3 | 25:11 | 14 | 31 |
| 3. |  |  | VfB Germania Halberstadt | 15 | 8-6-1 | 29:14 | 15 | 30 |
| 4. | |  | FC Erzgebirge Aue II | 15 | 8-3-4 | 23:11 | 12 | 27 |
| 5. | |  | FC Carl Zeiss Jena II | 17 | 7-5-5 | 31:24 | 7 | 26 |
| 6. | |  | FC Rot-Weiß Erfurt II | 14 | 7-4-3 | 24:20 | 4 | 25 |
| 7. | |  | FSV 63 Luckenwalde | 16 | 5-5-6 | 31:34 | -3 | 20 |
| 8. | |  | FC Sachsen Leipzig | 15 | 6-2-7 | 13:20 | -7 | 20 |
| 9. | |  | FSV Zwickau | 15 | 5-4-6 | 18:19 | -1 | 19 |
| 10. | |  | FSV Wacker 03 Gotha | 16 | 5-3-8 | 24:29 | -5 | 18 |
| 11. | |  | SC Borea Dresden | 14 | 4-5-5 | 17:21 | -4 | 17 |
| 12. | |  | SG Dynamo Dresden II | 15 | 5-1-9 | 21:27 | -6 | 16 |
| 13. | |  | 1. FC Lok Leipzig | 13 | 3-5-5 | 20:21 | -1 | 14 |
| 14. | |  | VfL Halle 96 | 15 | 3-3-9 | 16:27 | -11 | 12 |
| 15. | |  | 1. FC Magdeburg II | 14 | 3-3-8 | 15:33 | -18 | 12 |
| 16. | |  | Chemnitzer FC II | 14 | 3-2-9 | 19:31 | -12 | 11 |