| Sa., 18.09.2010 | FC Erzgebirge Aue II - SC Borea Dresden | 0:1 |
| Sa., 18.09.2010 | 1. FC Magdeburg II - SG Dynamo Dresden II | 1:0 |
| So., 19.09.2010 | FSV Wacker 03 Gotha - 1. FC Lok Leipzig | 3:2 |
| So., 19.09.2010 | VfL Halle 96 - Chemnitzer FC II | 4:2 |
| So., 19.09.2010 | FSV Zwickau - FSV 63 Luckenwalde | 3:1 |
| So., 19.09.2010 | VfB Auerbach - FC Carl Zeiss Jena II | 2:1 |
| So., 19.09.2010 | FC Sachsen Leipzig - FC Rot-Weiß Erfurt II | 0:0 |
| So., 19.09.2010 | FSV Budissa Bautzen - VfB Germania Halberstadt | 0:0 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | FSV Budissa Bautzen | 6 | 4-2-0 | 9:2 | 7 | 14 |
| 2. |  |  | VfB Auerbach | 6 | 4-1-1 | 8:7 | 1 | 13 |
| 3. |  |  | VfB Germania Halberstadt | 6 | 3-2-1 | 9:3 | 6 | 11 |
| 4. | |  | FSV Zwickau | 6 | 3-2-1 | 10:6 | 4 | 11 |
| 5. | |  | FSV 63 Luckenwalde | 6 | 2-3-1 | 13:9 | 4 | 9 |
| 6. | |  | FC Rot-Weiß Erfurt II | 6 | 2-3-1 | 10:8 | 2 | 9 |
| 7. | |  | FC Sachsen Leipzig | 5 | 2-2-1 | 4:5 | -1 | 8 |
| 8. | |  | FC Erzgebirge Aue II | 6 | 2-1-3 | 9:6 | 3 | 7 |
| 9. | |  | FC Carl Zeiss Jena II | 6 | 2-1-3 | 8:8 | 0 | 7 |
| 10. | |  | SG Dynamo Dresden II | 6 | 2-1-3 | 7:7 | 0 | 7 |
| 11. | |  | FSV Wacker 03 Gotha | 6 | 2-1-3 | 9:10 | -1 | 7 |
| 12. | |  | VfL Halle 96 | 6 | 1-2-3 | 7:9 | -2 | 5 |
| 13. | |  | SC Borea Dresden | 5 | 1-2-2 | 4:9 | -5 | 5 |
| 14. | |  | 1. FC Magdeburg II | 6 | 1-2-3 | 5:13 | -8 | 5 |
| 15. | |  | 1. FC Lok Leipzig | 4 | 0-3-1 | 6:7 | -1 | 3 |
| 16. | |  | Chemnitzer FC II | 6 | 0-2-4 | 6:15 | -9 | 2 |