| Di., 14.12.1999 | Chemnitzer FC - VfL Bochum | 3:3 |
| Di., 14.12.1999 | Hannover 96 - Stuttgarter Kickers | 2:1 |
| Di., 14.12.1999 | 1. FC Nürnberg - Tennis Borussia Berlin | 2:0 |
| Mi., 15.12.1999 | SC Fortuna Köln - SV Waldhof Mannheim | 1:5 |
| Mi., 15.12.1999 | FC St. Pauli - 1. FC Köln | 1:2 |
| Mi., 15.12.1999 | Alemannia Aachen - Rot-Weiß Oberhausen | 0:0 |
| Mi., 15.12.1999 | Karlsruher SC - SpVgg Greuther Fürth | 0:1 |
| Mi., 15.12.1999 | FSV Mainz 05 - Borussia Mönchengladbach | 0:0 |
| Mi., 15.12.1999 | FC Energie Cottbus - Kickers Offenbach | 5:0 |
| Sp. | S-U-N | Tore | Diff. | P | ||||
|---|---|---|---|---|---|---|---|---|
| 1. |  |  | 1. FC Köln | 16 | 11-4-1 | 35:11 | 24 | 37 |
| 2. | |  | FC Energie Cottbus | 16 | 10-1-5 | 36:17 | 19 | 31 |
| 3. |  |  | 1. FC Nürnberg | 16 | 8-3-5 | 27:27 | 0 | 27 |
| 4. |  |  | Tennis Borussia Berlin | 16 | 6-7-3 | 24:19 | 5 | 25 |
| 5. | |  | VfL Bochum | 16 | 7-3-6 | 28:25 | 3 | 24 |
| 6. | |  | Chemnitzer FC | 16 | 6-5-5 | 27:22 | 5 | 23 |
| 7. | |  | Alemannia Aachen | 16 | 6-5-5 | 25:30 | -5 | 23 |
| 8. | |  | Hannover 96 | 16 | 6-4-6 | 23:21 | 2 | 22 |
| 9. | |  | FSV Mainz 05 | 16 | 5-7-4 | 19:19 | 0 | 22 |
| 10. | |  | SpVgg Greuther Fürth | 16 | 5-7-4 | 11:14 | -3 | 22 |
| 11. | |  | SV Waldhof Mannheim | 16 | 5-5-6 | 23:24 | -1 | 20 |
| 12. | |  | Borussia Mönchengladbach | 16 | 4-6-6 | 19:21 | -2 | 18 |
| 13. | |  | FC St. Pauli | 16 | 4-6-6 | 17:21 | -4 | 18 |
| 14. | |  | Stuttgarter Kickers | 16 | 4-5-7 | 24:31 | -7 | 17 |
| 15. | |  | Rot-Weiß Oberhausen | 16 | 3-7-6 | 13:18 | -5 | 16 |
| 16. | |  | SC Fortuna Köln | 16 | 3-6-7 | 12:24 | -12 | 15 |
| 17. | |  | Karlsruher SC | 16 | 2-7-7 | 20:25 | -5 | 13 |
| 18. | |  | Kickers Offenbach | 16 | 2-6-8 | 11:25 | -14 | 12 |